Discover our company’s Lyophilizer, equipped with advanced features for laboratory, home use, industrial, and pilot-scale freeze drying applications. Learn about its specifications, benefits, and applications. Contact us today for the best freeze drying solution.
Welcome to our company’s advanced lyophilizer, offering innovative solutions for a wide range of applications. Our state-of-the-art equipment is specifically designed to cater to the diverse needs of laboratories, homes, industrial facilities, and pilot-scale operations. In this detailed page, we will explore the different specifications and capabilities of our versatile freeze dryers, highlighting their benefits and applications. Contact us today to discover efficient freeze drying solutions tailored to your requirements.
Lyophilizer Types
Freeze Dryer TypesLyophilizer DisplayLyophilizer Real ShotLyophilizer Real ShotLyophilizer Packing
Stages of freeze drying
There are four stages in the complete freeze drying process: pretreatment, freezing, primary drying, and secondary drying.
Pretreatment
Pretreatment includes any method of treating the product prior to freezing. This may include concentrating the product, formulation revision (i.e., addition of components to increase stability, preserve appearance, and/or improve processing), decreasing a high-vapor-pressure solvent, or increasing the surface area.
Freezing and annealing
During the freezing stage, the material is cooled below its triple point, the temperature at which the solid, liquid, and gas phases of the material can coexist. This ensures that sublimation rather than melting will occur in the following steps.
Structurally sensitive goods
In the case of goods where preservation of structure is required, like food or objects with formerly-living cells, large ice crystals will break the cell walls which can result in increasingly poor texture and loss of nutritive content. In this case, the freezing is done rapidly, in order to lower the material to below its eutectic point quickly, thus avoiding the formation of large ice crystals. Usually, the freezing temperatures are between −50 °C (−58 °F) and −80 °C (−112 °F).
Primary drying
During the primary drying phase, the pressure is lowered (to the range of a few millibars), and enough heat is supplied to the material for the ice to sublimate. The amount of heat necessary can be calculated using the sublimating molecules’ latent heat of sublimation. In this initial drying phase, about 95% of the water in the material is sublimated.
Secondary drying
The secondary drying phase aims to remove unfrozen water molecules, since the ice was removed in the primary drying phase. This part of the freeze-drying process is governed by the material’s adsorption isotherms. In this phase, the temperature is raised higher than in the primary drying phase, and can even be above 0 °C (32 °F), to break any physico-chemical interactions that have formed between the water molecules and the frozen material.
After the freeze-drying process is complete, the vacuum is usually broken with an inert gas, such as nitrogen, before the material is sealed. At the end of the operation, the final residual water content in the product is extremely low, around 1% to 4%.
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Our laboratory freeze dryers are designed for small-scale applications in research laboratories, pharmaceutical development, and quality control. These compact units provide precise temperature control, efficient drying cycles, and user-friendly interfaces, making them ideal for limited laboratory space.
ZLGJ Series Lyophilizer Product ComponentZLGJ-10 Series LyophilizerZLGJ-12 ZLGJ-18 Series Lyophilizer
Compact design: Our laboratory freeze dryers optimize space utilization while maximizing functionality.
Precise temperature control: Ensure accurate temperature control throughout the freeze drying process for reproducible results.
Efficient drying cycles: Advanced cooling systems optimize drying processes, reducing cycle times and increasing productivity.
User-friendly interface: Intuitive interfaces enable easy operation and monitoring, providing flexibility and control.
Wide range of accessories: Various accessories, such as shelves, vials, and trays, accommodate different sample types and sizes.
Applications
Research laboratories: Preserve sensitive biological samples like enzymes, proteins, and vaccines for long-term storage and analysis.
Pharmaceutical development: Facilitate formulation and development of drugs, enabling efficient production and storage of pharmaceutical products.
Quality control: Achieve accurate and consistent drying of samples for reliable quality control processes in various industries.
Pilot-Scale
Our pilot-scale freeze dryers bridge the gap between laboratory-scale and industrial-scale freeze drying. These versatile units are designed for process development, optimization, and small-scale production. With flexible configurations and advanced features, they allow for seamless scale-up from lab to industrial production, ensuring consistent results and efficient processes.
Process optimization: Facilitate comprehensive process optimization, including cycle development, product formulation, and drying parameter adjustments.
Modular design: Flexibility in adapting to different product types, volumes, and process requirements.
Advanced process control: Real-time monitoring and data logging capabilities for process analysis and optimization.
Applications
Process development: Facilitate the development and optimization of freeze drying processes for pharmaceuticals, biologics, and specialty chemicals.
Small-scale production: Support small-scale production runs, clinical trials, or limited quantities of specialty products.
Technology transfer: Ensure consistency and reliability during the transition from laboratory to industrial-scale production.
Our advanced freeze drying equipment offers innovative solutions for various applications. Whether you require precise control in the laboratory, convenient preservation at home, large-scale industrial capabilities, or process development flexibility, our freeze dryers are equipped with advanced features to meet your specific needs. Contact us today to explore our range of freeze dryers and discover efficient freeze drying solutions tailored to your requirements.
Home Use
Our home use freeze dryers bring the benefits of freeze drying technology to your home. These compact units provide an easy and convenient way to preserve food, extend its shelf life, and retain its nutritional value. Whether you’re a home cook, gardener, or outdoor enthusiast, our freeze dryers offer a simple solution for preserving your favorite ingredients and homemade creations.
Compact and portable: Fit seamlessly into your kitchen or pantry and easily transportable for outdoor activities.
User-friendly operation: Intuitive controls and pre-set programs make the freeze drying process simple and accessible.
Energy-efficient: Designed to be energy-efficient, reducing operating costs while maintaining optimal performance.
Quiet operation: Operate quietly, ensuring a peaceful environment in your home.
Applications
Food preservation: Preserve fruits, vegetables, meats, herbs, and prepared meals while maintaining taste, texture, and nutritional value.
Culinary creations: Create instant meals, camping food, and snacks with ease.
Gardening: Preserve garden produce like herbs, fruits, and vegetables for year-round enjoyment and minimal waste.
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Industrial-Scale
Our industrial freeze dryers meet the demanding requirements of large-scale freeze drying operations in industries such as pharmaceuticals, biotechnology, and food processing. These robust and high-capacity units offer superior performance, reliability, and flexibility, ensuring efficient and cost-effective freeze drying processes.
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